Erythema Nodosum

Mononucleosis, also referred to as glandular fever, is a common ailment most frequently associated with teens and young adults. A viral illness caused by the Epstein-Barr virus, mono is spread through saliva, hence the well-known title "The Kissing Disease." In fact, mono can be spread from coughing, sneezing or close contact, using common eating utensils or even towels.

Common Symptoms Associated With Mono

The symptoms of mono are very common and it is often difficult to make a diagnosis based on the symptoms alone. The most frequent presentation of the disease is a low-grade headache that's hung on for several days, lethargy and lack of appetite. General malaise, fatigue and muscle soreness precede a sore throat, fever (with accompanying chills and sweats), and tender, swollen lymph nodes. It can be an uncomfortable few weeks until the virus has passed.

There are other problems which can manifest with mononucleosis including enlarged spleen and liver. In extreme cases, these alone can become severe situations so it is important that the illness is addressed as early as possible.  There can also be complications in the brain and heart-this is nothing to fool with.

The Inflammation Is Inside And Outside As Well

Another condition which can present as a result of mononucleosis is a type of skin inflammation called erythema nodosum, also called EN. Occurring in the fatty layer of the skin, it results in lumps which are painful and tender, often appearing as reddish bumps on the front of the legs below the knees. EN can resolve itself within the period of time it takes for the person to recover from mono, with the nodular inflammations slowly shrinking down eventually leaving marks that look like bruising on the legs.

Diagnosis and Treatment of Erythema Nodosum

As a rule, it is relatively easy for a doctor to diagnose erythema nodosum by examining the patient and making note of the typical tight-skinned, red area with lesions and a bruised appearance. Sometimes a biopsy is done for confirmation; however, it is usually not necessary. The way EN is managed is through the treatment of the condition which brought it on in the first place. Also, treatment is directed toward the inflamed areas on the skin. The most common treatments are anti-inflammatory drugs such as cortisone, either taken by mouth or injection. Even though it is disturbing and sometimes painful, erytema nodosum does not affect internal organs and, in the long run, it does usually heal well with lesions of EN spontaneously resolving over a period of weeks or sometimes months.

EN Can Hang Around For Years

There is another side to EN which can occur wherein the condition becomes chronic and may last for years, long after the originating illness is gone. Some people who contract mononucleosis experience erythema nodosum as a result of the infection and end up with EN, living it with for many years. For those who suffer with chronic EN, sometimes cortisone or steroid treatments help relieve the symptoms and often there is little left to do other than live with the condition.